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Setmelanotide Raw powder

Setmelanotide is a pro-opiomelanocortin derived peptide that is an agonist of MC4R. It is an approximately 20-fold more potent MC4R agonist than endogenous α-melanocyte-stimulating hormone with an EC 50 of 0.27 nM. By direct activation of MC4R, upstream genetic defects in MC4R signaling fail to suppress satiety and reduce food intake, leading to weight loss. MC4R is a 332-amino acid G-protein coupled receptor (G-PCR). Setmelanotide is an atypical bisteric ligand that interacts with orthomeric and putative allosteric binding sites with high affinity and specificity. It is a white powder and needs to be stored in a low temperature environment.
Product Status:White powder
Purity:98%
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  • Product Description

Setmelanotide Raw Powder: Premium Quality for Rare Genetic Obesity Treatment

Hangzhou Go Top Peptide Biotech Co.,Ltd. is a leading manufacturer and supplier of high-quality product. Our state-of-the-art peptide synthesis technology and experienced team of scientists ensure top-notch purity and consistency in every batch. We offer tailored solutions for pharmaceutical companies and research institutions developing treatments for rare genetic obesity disorders.

Setmelanotide product image,

Product Introduction

Setmelanotide Raw powder is a potent melanocortin-4 receptor (MC4R) agonist used in the treatment of rare genetic obesity conditions. This synthetic peptide mimics the action of α-melanocyte-stimulating hormone (α-MSH), helping to regulate appetite and energy expenditure. Our premium-grade raw powder is ideal for pharmaceutical formulation and research applications.

Key Details:

  • CAS: 920014-72-8
  • Sequence: Ac-Arg-c(Cys-D-Ala-His-D-Phe-Arg-Trp-Cys)-NH2
  • Molecular formula: C49H68N18O9S2
  • Molecular weight: 1117.309

Setmelanotide peptide synthesis,

Specifications:

ParameterSpecification
AppearanceWhite to off-white powder
Purity≥98% (HPLC)
Water Content≤5.0%
Acetate≤10.0%
Specific Optical Rotation-50° to -60°

Uses and Applications

Setmelanotide Raw powder is primarily used in the development of therapies for:

  • Proopiomelanocortin (POMC) deficiency obesity
  • Leptin receptor (LEPR) deficiency obesity
  • Bardet-Biedl syndrome
  • Alström syndrome

Setmelanotide white powder,

It's also valuable for research into MC4R signaling and metabolic disorders.

Company Introduction

Hangzhou Go Top Peptide Biotech Co.,Ltd. is a trusted global supplier of high-quality peptides and APIs. With over a decade of experience, we specialize in custom peptide synthesis and bulk production for the pharmaceutical and biotech industries.

Our Advantages

  • GMP-certified facilities ensuring consistent quality
  • Comprehensive regulatory documentation support
  • Flexible scale-up capabilities from grams to kilograms
  • Rigorous quality control and stability testing
  • Fast turnaround times and reliable global shipping

Laboratory and Factory

Setmelanotide laboratory,

Our state-of-the-art facilities include:

  • Advanced peptide synthesizers and purification equipment
  • Analytical labs with HPLC, LCMS, and NMR capabilities
  • Clean rooms for aseptic processing
  • Dedicated QC and stability testing areas

Packaging and Shipping

We offer secure, temperature-controlled packaging options to maintain product integrity during transit. Our logistics team ensures prompt, compliant global shipping with full tracking.

Certification

  • ISO 9001:2015 certified
  • GMP compliance
  • US FDA registered facility
  • EU REACH compliant

, Setmelanotide peptide customization

FAQ

Q: What is the minimum order quantity for product?
A: We offer flexible quantities starting from 1 gram for research purposes, with bulk orders available for commercial production.

Q: Can you provide stability data for product?
A: Yes, we offer comprehensive stability data and can conduct custom stability studies upon request.

Q: Do you offer technical support for formulation development?
A: Absolutely. Our team of experts can provide guidance on formulation, analytical methods, and regulatory requirements.

Q: What documentation is provided with product orders?
A: Each order includes a Certificate of Analysis, MSDS, and full regulatory support documentation as needed.

Contact Us

Ready to order or have questions about our Setmelanotide Raw powder? Our team is here to help. Reach out to us at sales1@gotopbio.com for personalized assistance and competitive quotes. Trust Hangzhou Go Top Peptide Biotech Co.,Ltd. for all your peptide API needs.

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