Delia radicum AKH,129204-82-6,Peptide synthesis,Peptide raw material company

PeptideName：Delia radicum AKH/129204-82-6/Peptide synthesis

Catalog No：GT-P2822

Sequence：Pyr-Leu-Thr-Phe-Ser-Pro-Asp-Trp-NH2

CAS Number：129204-82-6

Molecular Formula：C47H62N10O13

Molecular Weight：975.05

Category：Delia radicum AKH,129204-82-6,Peptide synthesis,Peptide raw material company

Description：Delia radicum AKH (full name: Delia radicum adipokinetic hormone, CAS number 129204-82-6), commonly known as "trehalose hormone" due to the presence of trehalose-related functional fragments in its molecular structure, belongs to the lipomokines (AKH) class of insect neuropeptides and is a key signaling molecule regulating energy metabolism in specific insects. Current research on the function of this hormone focuses on the regulation of insect energy metabolism. On the one hand, it can activate specific receptors on the surface of fat body cells; on the other hand, it can regulate glycogenolysis in fat bodies or other tissues, promoting the synthesis and release of trehalose, the main form of "glucose" in insect hemolymph.

Specifications

Apperance: White to off-white powder

Purity(HPLC): ≥98.0%

Single Impurity: ≤2.0%

Acetate Content(HPLC): 5.0%～12.0%

Water Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.

FAQ：

Which end is best for my research?

By default, the peptide ends with an N-terminal free amino group and a C-terminal free carboxyl group. The peptide sequence often represents the sequence of the mother protein. In order to be closer to the mother protein, the end of the peptide often needs to be closed, that is, n-terminal acetylation and C-terminal amidation. This modification avoids the introduction of excess charge, and also makes it more able to prevent exonucliase action, so that the peptide is more stable.

What problems should be paid attention to in the storage process?

The peptide you received was packaged in lyophilized powder. Peptides are hydrophilic, and absorption of water will reduce the stability of the peptide and reduce the peptide content. Please pay attention to the following: first, with desiccants, stored in a dry environment. Second, once received, please immediately put into the freezer -20℃ storage, in order to maintain maximum stability. Third, avoid the use of no automatic frost function of the freezer. Changes in humidity and temperature can affect the stability of peptides. Fourth, the external temperature during transportation does not affect the validity and quality of peptides.

How do you dissolve polypeptides?

The solubility of polypeptide depends mainly on its primary and secondary structure, the nature of modification label, solvent type and final concentration. If the peptide is insoluble in water, ultrasound can help dissolve it. For basic peptide, it is recommended to dissolve with 10% acetic acid; For acidic peptides, dissolution with 10%NH4HCO3 is recommended. Organic solvents can also be added to insoluble polypeptides. The peptide is dissolved in the least amount of organic solvent (e.g., DMSO, DMF, isopropyl alcohol, methanol, etc.). It is highly recommended that the peptide be dissolved in the organic solvent first and then slowly added to water or other buffer until the desired concentration.

If a Delia radicum AKH is 98% pure, what is 2%?

Two percent of the composition was truncated or deleted sequence fragments.

I live abroad, and it will take several days for delivery and customs clearance. Will this affect my research?

You receive the peptides in lyophilized powder packages, and peptides can usually be stored at room temperature without damage. Please freeze and store immediately after receipt.