N-Ac Selank Amidate/129954-34-3/selank peptide
- Product Description
PeptideName：N-Ac Selank Amidate/129954-34-3/selank peptide
Catalog No：GT-A022
Sequence：Thr-Lys-Pro-Arg-Pro-Gly-Pro
CAS Number：129954-34-3
Molecular Formula：C33H57N11O9
Molecular Weight：751.89
Category：N-Ac Selank Amidate,129954-34-3,Peptide synthesis,Peptide raw material company
Description：N-Ac Selank Amidate exerts stable anxiolytic, anti-stress, and cognitive-protective effects by regulating the balance of neurotransmitters in the brain, inhibiting the release of inflammatory factors, and enhancing BDNF expression and neurotrophic activity.It also modulates immune function and ameliorates neurodegenerative-related injuries, being widely used in basic and translational research in the fields of anxiety disorders, stress-related diseases, neuroimmunomodulation, and cognitive repair, and holds significant value in psychoneuropharmacological research.
Specifications
Apperance: White to off-white powder
Purity(HPLC): ≥98.0%
Single Impurity: ≤2.0%
Acetate Content(HPLC): 5.0%～12.0%
Water Content (Karl Fischer): ≤10.0%
Peptide Content: ≥80.0%
Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.
FAQ：
How do you dissolve polypeptides?
The solubility of polypeptide depends mainly on its primary and secondary structure, the nature of modification label, solvent type and final concentration. If the peptide is insoluble in water, ultrasound can help dissolve it. For basic peptide, it is recommended to dissolve with 10% acetic acid; For acidic peptides, dissolution with 10%NH4HCO3 is recommended. Organic solvents can also be added to insoluble polypeptides. The peptide is dissolved in the least amount of organic solvent (e.g., DMSO, DMF, isopropyl alcohol, methanol, etc.). It is highly recommended that the peptide be dissolved in the organic solvent first and then slowly added to water or other buffer until the desired concentration.
Can you give some advice on the design of phosphorylated peptides?
As the length increases, the binding efficiency gradually decreases from the phosphorylated amino acid onwards. The synthesis direction is from the C terminal to the N terminal. It is recommended that the residues after the phosphorylated amino acid should not exceed 10, that is, the number of amino acid residues before the phosphorylated amino acid from the N terminal to the C terminal should not exceed 10.
How is my peptide transported? What test reports are provided?
All freeze-dried polypeptides are usually stored in special containers of 2 ml or 10ml with original analytical data and synthesis reports containing important information such as sequence, molecular weight, purity, weight, and number of the polypeptide.
If a N-Ac Selank Amidate is 98% pure, what is 2%?
Two percent of the composition was truncated or deleted sequence fragments.
How do you determine if a peptide is looped?
We use the Ellman reaction to test whether the ring formation is complete. If the Ellman test is positive (yellow), the ring reaction is incomplete. If the test results are negative (not yellow), the ring reaction has been complete. We do not provide the analysis report of cyclization identification for our clients. Generally, there will be a description of Ellman's test results in the QC report.
