Tertomotide/922174-60-5/Tertomotide Peptide
- Product Description
PeptideName：Tertomotide/922174-60-5/Tertomotide Peptide
Catalog No：GT-L011
Sequence：EARPALLTSRLRFIPK
CAS Number：122933-59-9
Molecular Formula：C85H146N26O21
Molecular Weight：1868.23
Category：Tertomotide,922174-60-5,Peptide synthesis,Peptide raw material company
Description：Tertomotide was initially developed as an anti-tumor vaccine by targeting telomerase, which is highly expressed in most tumor cells. It is designed to specifically kill TERT-expressing cancer cells by activating cytotoxic T lymphocytes, and has been widely investigated in clinical immunotherapy studies for malignant tumors such as pancreatic cancer and prostate cancer.
Specifications
Apperance: White to off-white powder
Purity(HPLC): ≥98.0%
Single Impurity: ≤2.0%
Acetate Content(HPLC): 5.0%～12.0%
Water Content (Karl Fischer): ≤10.0%
Peptide Content: ≥80.0%
Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.
FAQ：
Which end is best for my research?
By default, the peptide ends with an N-terminal free amino group and a C-terminal free carboxyl group. The peptide sequence often represents the sequence of the mother protein. In order to be closer to the mother protein, the end of the peptide often needs to be closed, that is, n-terminal acetylation and C-terminal amidation. This modification avoids the introduction of excess charge, and also makes it more able to prevent exonucliase action, so that the peptide is more stable.
How is my peptide transported? What test reports are provided?
All freeze-dried polypeptides are usually stored in special containers of 2 ml or 10ml with original analytical data and synthesis reports containing important information such as sequence, molecular weight, purity, weight, and number of the polypeptide.
If a Tertomotide is 98% pure, what is 2%?
Two percent of the composition was truncated or deleted sequence fragments.
How do you determine if a peptide is looped?
We use the Ellman reaction to test whether the ring formation is complete. If the Ellman test is positive (yellow), the ring reaction is incomplete. If the test results are negative (not yellow), the ring reaction has been complete. We do not provide the analysis report of cyclization identification for our clients. Generally, there will be a description of Ellman's test results in the QC report.
