- Product Description
Abaloparatide peptide customization，247062-33-5:
At Hangzhou Go Top Peptide Biotech Co., Ltd., we're proud to be a leading manufacturer and supplier of Larazotide. Our state-of-the-art facilities and expert team ensure the highest quality product for your pharmaceutical needs. With our commitment to excellence and innovation, we offer unparalleled advantages in peptide synthesis and production.
Product Introduction
Because of its promising osteogenic activity, abaloparatide, a selective activator of the parathyroid hormone receptor (PTH1 receptor), has been advanced in clinical development for the treatment of osteoporosis in postmenopausal women at high risk for fractures.
Key Product Details
1.CAS: 247062-33-5
2.Sequence: H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-N-Me-Ala-Lys-Leu-His-Thr-Ala-NH2
3.Molecular formula: C174H300N56O49
4.Molecular weight: 3960.5896
Specifications
Parameter | Specification |
Appearance | White to off-white powder |
Purity | ≥98% |
Solubility | Soluble in water |
Storage | -20°C, protected from light |
Uses and Applications
Abaloparatide peptide customization has shown promise in:
Apapatide is a peptide composed of 34 amino acid residues. It is a new parathyroid hormone-related peptide (PTHrP) developed by RadiusHealth. It is a potent and selective activator of the PTH-I receptor, which can increase bone mineral content, bone density and bone strength, promote bone formation. It has been approved for marketing by the FDA on April 28, 2017, under the trade name Tymlos. "Subcutaneous administration of apapatide for the treatment of osteoporosis in postmenopausal women who are at risk for fracture or who do not respond to other treatment agents is effective in reducing the rate of new vertebral and nonvertebral fractures." Compared with teriparatide, abapatide was more effective in reducing the incidence of fractures and hypercalcemia.
Company Introduction
Hangzhou Go Top Peptide Biotech Co., Ltd. is a global leader in peptide synthesis and manufacturing. We combine cutting-edge technology with scientific expertise to deliver high-quality peptides for pharmaceutical research and development.
Our Advantages
1.GMP-certified production facilities
2.Rigorous quality control systems
3.Fast turnaround times
4.Global delivery network
5.Cost-effective solutions
6.Comprehensive technical support
Laboratory and Factory
Our state-of-the-art laboratory and factory are equipped with the latest peptide synthesis technology. Our facilities adhere to strict quality standards, ensuring consistent, high-purity Larazotide production.
Packaging and Shipping
We offer secure, temperature-controlled packaging to maintain product integrity. Our global logistics network ensures timely delivery to your facility, wherever you are in the world.
Certification
Hangzhou Go Top Peptide Biotech Co., Ltd. is proud to have passed ISO 9001:2015 quality management system certification, demonstrating our commitment to excellence and regulatory compliance.
FAQ
1.Which end is best for my research?
By default, the peptide ends with an N-terminal free amino group and a C-terminal free carboxyl group. The peptide sequence often represents the sequence of the mother protein. In order to be closer to the mother protein, the end of the peptide often needs to be closed, that is, n-terminal acetylation and C-terminal amidation. This modification avoids the introduction of excess charge, and also makes it more able to prevent exonucliase action, so that the peptide is more stable.
2.Which modified labeled polypeptides can be synthesized in Chinese peptide?
Our company provides a variety of modified peptide labeling, such as acetylation, biotin labeling, phosphorylation modification, fluorescence modification, can also be customized according to your special needs.
3.How do you dissolve polypeptides?
The solubility of polypeptide depends mainly on its primary and secondary structure, the nature of modification label, solvent type and final concentration. If the peptide is insoluble in water, ultrasound can help dissolve it. For basic peptide, it is recommended to dissolve with 10% acetic acid; For acidic peptides, dissolution with 10%NH4HCO3 is recommended. Organic solvents can also be added to insoluble polypeptides. The peptide is dissolved in the least amount of organic solvent (e.g., DMSO, DMF, isopropyl alcohol, methanol, etc.). It is highly recommended that the peptide be dissolved in the organic solvent first and then slowly added to water or other buffer until the desired concentration.
Contact Us
Ready to order or have questions about our Larazotide? We're here to help! Contact our expert team at sales1@gotopbio.com for personalized assistance and to discuss how we can meet your peptide needs.
Experience the Hangzhou Go Top Peptide Biotech difference – where quality, innovation, and customer satisfaction meet. Let's advance gastrointestinal health research together with our premium product.
